Daxxify
Daxxify is the long-lasting one. An FDA-approved wrinkle relaxer built on a unique peptide-powered formulation, it is approved for frown lines between the brows and is also used to soften forehead lines and crow's feet the way Botox and Dysport are, but the result holds for about six months for most patients, sometimes longer. Fewer appointments, more months of smooth.
What isDaxxify?
Daxxify is a neuromodulator: it temporarily blocks the nerve signals that tell specific facial muscles to contract, so the skin creased by that constant motion smooths out and new lines are slower to form. The mechanism is the same one behind Botox, Dysport, and Xeomin. The formulation is not.
Daxxify is stabilized by a peptide rather than the human or animal-based additives traditional wrinkle relaxers use, and that peptide technology is what extends its life. Where most neuromodulators need refreshing every three to four months, Daxxify holds for about six months for most patients, sometimes longer.
The appointment itself is the same quick visit: 10 to 20 minutes, a few precise injections, no anesthesia required and no downtime. First improvement shows within a few days and the full result settles in one to two weeks.
Who is Daxxify for?
Daxxify is for people who love what a wrinkle relaxer does and want it to last longer.
Daxxify, Botox, Dysport, Xeomin, and Jeuveau all relax the same muscles; the differences are in spread, onset, and staying power. Our injectors work with all of them and will tell you honestly which one fits your face and your calendar.
You have expression lines
Frown lines between the brows, horizontal forehead lines, or crow's feet around the eyes.
You want longer-lasting results
Daxxify holds for about six months for most patients, roughly twice the typical interval of traditional relaxers.
You prefer fewer appointments
Two visits a year can maintain the result many patients previously needed three or four visits to keep.
You want a non-surgical option
A few small injections in a short office visit, with nothing to recover from.
You have realistic expectations
Results are still temporary; they just last longer between refreshes.
Where Daxxifyworks
Daxxify treats the classic expression zones of the upper face, and its formulation is gentle enough for the delicate skin around the eyes. Other areas may be an option case by case at your consultation.
Select an area on the figure to see what Daxxify does there.
Daxxify, frown lines1 / 2
What Daxxifysmoothing looks like.
These are manufacturer before-and-after images that appeared on the practice's previous website. They are not photographs of our patients. Your own plan is designed at your consultation. Drag the handle to compare.
See the full galleryIndividual results vary. These are manufacturer before-and-after images that appeared on the practice's previous website, not photographs of our patients, and are not a guarantee of your own outcome.
Whatto expect.
Book a consultationDaxxify is priced by the areas treated and the amount used, so we give a personalized quote at your consultation.
A quick office visit; the injections themselves take well under fifteen minutes. Topical numbing may be available if you want it.
Straight back to your day. Mild, temporary redness or swelling at the injection points is the most common effect.
First improvement within a few days, full result in one to two weeks, lasting about six months for most patients, sometimes longer.
Frequently asked questions
How is Daxxify different from Botox?
They relax muscles the same way, but Daxxify is stabilized by a peptide-based formulation designed to last significantly longer, which means fewer treatments per year to hold the same result.
How long does Daxxify last?
About six months for most patients, and sometimes longer. That is roughly twice the typical interval of traditional wrinkle relaxers.
What makes the formulation different?
Daxxify uses peptide-powered technology to stabilize the active molecule, eliminating the need for the human or animal-based additives found in traditional neuromodulators.
Does Daxxify look natural?
Yes. Properly placed, it softens the lines while your expressions stay yours: refreshed, not frozen.
How soon will I see results?
Initial improvement appears within a few days, with the full result visible in one to two weeks.
Is there any downtime after Daxxify?
No. You can return to normal activities immediately. Mild redness or swelling at the injection sites fades quickly.
What areas can Daxxify treat?
Daxxify is FDA-approved for frown lines between the eyebrows. Like Botox and Dysport, it is also commonly used off-label for forehead lines and crow's feet, with other areas possible case by case on your provider's recommendation.
When should I start using Daxxify?
Many patients start preventatively in their late 20s or 30s; others come in later to soften lines that have already settled in. Both approaches work.
Does the treatment hurt?
The injections use a very fine needle and take only minutes. No anesthesia is required, and a topical numbing option may be available if you prefer.
Where to next
Related treatment
Botox
Soften lines and wrinkles.
Explore the treatmentRelated concern
Lines & Wrinkles
Motion lines and creases that stay put
Start from the concernWorth reading
Can Daxxify Treat Crow’s Feet and Smile Lines?
Want smoother crow’s feet and smile lines? Learn how Daxxify treats eye wrinkles with long-lasting results.
Read the answerAsk about injectables.
Tell us what you would like to soften or restore. We will come back with which product fits, how long it lasts, and what to expect at your first visit.
Your details go straight to our Montgomery Road front desk and are never shared. A team member replies during office hours, usually the same day.
Ready when you are.
Book a consultation at our Montgomery Road office, or call and we will help you decide where to start.
Medically reviewed by Shalini Gupta, MD, Harvard-trained dermatologist and founder of The Dermatology, Laser & Vein Center. Last reviewed September 2026. This page is for education and is not a substitute for a personalized medical consultation.